GLP-1 Weight Loss Injections in the UK

Everything you need to know about Wegovy, Ozempic and Mounjaro

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What Are GLP-1 Injections?

GLP-1 receptor agonists are a group of medicines designed to mimic natural gut hormones. By slowing digestion, controlling appetite, and improving blood sugar levels, they help patients lose weight and maintain it more effectively than traditional diet-only approaches.

How Do GLP-1s Work?

GLP-1 medicines such as Wegovy, Ozempic and Mounjaro act on receptors in the brain and digestive system. They make you feel fuller for longer, reduce cravings, and stabilise blood sugar. This creates a natural calorie reduction without extreme diets.

Key Benefits

NHS vs Private Access in the UK

The NHS prescribes GLP-1s under strict rules. Eligibility usually requires a BMI of 35+ and weight-related health conditions like type 2 diabetes or sleep apnoea. Waiting times can be long and supply is often limited.

Private clinics offer faster access with broader eligibility. Many patients choose private weight loss injections to avoid delays and access flexible treatment programmes tailored to their lifestyle.

Costs of GLP-1 Treatment

On the NHS, treatment is funded if you meet criteria. In private clinics, prices vary depending on the brand and dose, but costs typically cover medical assessments, prescriptions and ongoing support. Rising demand worldwide has pushed prices up, making affordability an important consideration.

Why Mounjaro Is Different

Mounjaro (tirzepatide) is the most effective GLP-1 treatment currently available in the UK. Unlike Wegovy and Ozempic, which only target the GLP-1 hormone, Mounjaro also activates GIP receptors. This dual mechanism provides enhanced appetite control and metabolic benefits.

Mounjaro injection UK Find Out if Mounjaro Is Right for You

Comparison: Mounjaro vs Wegovy vs Ozempic

Medication Active Ingredient How It Works Average Weight Loss UK Availability
Mounjaro Tirzepatide Dual action (GLP-1 + GIP) Up to 22% Private clinics (expanding), NHS rollout coming
Wegovy Semaglutide GLP-1 only ~15% NHS (strict criteria) & private providers
Ozempic Semaglutide GLP-1 only ~12% Mainly for diabetes; some off-label use
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Real-Life Results

Patients in the UK report improved appetite control, more energy and sustainable weight loss. Clinical studies confirm these experiences: Mounjaro users lost an average of 22% body weight, Wegovy around 15%, and Ozempic about 12% when used consistently with lifestyle changes.

Side Effects

Like any medication, GLP-1 injections may cause side effects. The most common include nausea, diarrhoea, constipation and mild fatigue, which usually ease as your body adjusts. Rare but serious risks exist, so professional guidance is essential.

Frequently Asked Questions

Do I need to taper if I stop?
You don’t always need to taper, but some prescribers recommend stepping down to reduce side effects.
Why are prices rising?
Global demand is high and UK suppliers are adjusting prices. Some patients are writing to MPs to highlight affordability concerns.
Can I get GLP-1s on the NHS?
Yes, but access is limited to those with a BMI of 35+ and related health conditions. Many choose private care for faster treatment.
Is Mounjaro more effective than Wegovy?
Yes. Mounjaro targets both GLP-1 and GIP, leading to greater average weight loss than Wegovy in trials.
What side effects should I expect?
Nausea, diarrhoea or constipation are common but usually temporary. Your prescriber will monitor you closely.
How fast will I see results?
Most people notice reduced appetite within weeks. Substantial weight loss occurs after 3–6 months of consistent treatment.
Do I need to stay on treatment forever?
Not necessarily. Some continue long-term, others stop once reaching a sustainable weight. It depends on your health needs.

Ready to Take the Next Step?

Discover if GLP-1 treatment is right for you. Speak with a UK prescriber today and start your personalised plan.

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